This coming Monday we will have the following talk from Jacint Sala, who is a PhD student with Dr. Estela Camara
Temporal lobe epilepsy from a network perspective
Temporal lobe epilepsy (TLE) is a frequent form of epilepsy with devastating consequences in different symptomatic domains; patients suffer from frequent seizures and face cognitive and emotional deficits. Resective surgery for drug-resistant TLE has proven to be an effective treatment to render some patients seizure free; however, not all patients show an improvement after the procedure, and the resection of temporal lobe structures can paradoxically increase the seizure frequency and the cognitive deficits that these patients usually present. In the past 20 years, approaching epilepsy as a brain network disease and identifying biomarkers beyond the temporal lobe has proven to be a promising tool in improving the selection and the prediction of prognosis of these patients after surgery. With our sample of patients with TLE that have been evaluated before and after surgery, we investigated the bilateral integrity of the hippocampal subfields and the functional connectivity of the temporal lobes revealing a relationship with seizure and neuropsychological outcome.
Location: https://ub-edu.zoom.us/j/94500494920